Search on: CRUSH SYNDROME 
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Descriptor English:   Crush Syndrome 
Descriptor Spanish:   síndrome de aplastamiento 
Descriptor Portuguese:   Síndrome de Esmagamento 
Synonyms English:   Crush Syndromes
Syndrome, Crush
Syndromes, Crush  
Tree Number:   C26.257.500
C26.797.240
Definition English:   Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia. 
See Related English:   Compartment Syndromes
 
History Note English:   91(75); was see under SHOCK, TRAUMATIC 1979-90; was see under KIDNEY FAILURE, ACUTE 1967-78; was see under ACUTE RENAL FAILURE 1963-66 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   3461 
Unique Identifier:   D003444 

Occurrence in VHL:
 

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